Session: Even Numbered Posters (The 22nd Annual Meeting of the American Society of Pediatric Hematology/Oncology)

Friday, April 24, 2009: 12:30 PM-1:45 PM

Hilton San Diego Bayfront

Genetically Reengineered K562 Cells (Antigen Presenting Cells, APC) Significantly Expand Cord Blood (CB) Natural Killer (NK) Cells for Use in Adoptive Cellular Immunotherapy
Jessica Hochberg, MD, Brenton Mar, MD, Janet Ayello, MS, Carmella van de Ven, MS, Angela Ricci, BA, Lalit Gurnani, Dario Campana, MD, PhD and Mitchell S. Cairo

102

Lung Function, Pulmonary Complications and Mortality after Allogeneic BMT in Children
Zühre Kaya, MD, Daniel J. Weiner, MD, Ahmet Gül, MS, Deniz Yilmaz, MD, Jason Rowan, RN and Rakesh K. Goyal, MD

104

The Efficacy of the Homeopathic Agent Traumeel S® in the Prevention and Treatment of Mucositis in Children Undergoing Stem Cell Transplantation
Susan F. Sencer, M.D., Tianni Zhou, Ph.D., Menachem Oberbaum, M.D., FFHom, Laurence S. Freedman, Ph.D., Thomas W. McLean, M.D., Indira Sahdev, M.D., John A. Ives, Ph.D. and Wayne B. Jonas, M.D.

106

High Dose Chemotherapy with Amifostine Chemoprotection and Autologous Stem Cell Transplantation for High Risk Ewing's Sarcoma
Sonata Jodele, MD, Stella M. Davies, MBBS, PhD, MRCP, Alexandra Filipovich, MD, Jack J. Bleesing, MD, PhD, Parinda A. Mehta, MD, John C. Breneman, MD, Ruth Lavigne, MD and John Perentesis, MD

108

Children's Coping with Hematopoietic Stem Cell Transplantation (HSCT): Results from the Journeys to Recovery Study
Michael W. Kent, MD, Sara J. Ratichek, MA, Mary Jo Kupst, PhD, Kristin Bingen, PhD, Christopher Recklitis, PhD, MPH, Grace Chang, MD, MPH, Hocine Tighiouart, MS, Norma Terrin, PhD and Susan K. Parsons, MD, MRP

110

Safety of Liposomal Cytarabine (Depocyt®) Prophylaxis in Pediatric Bone Marrow Transplant (BMT) Recipients with Acute Leukemia (AL) and Non Hodgkin Lymphoma (NHL) at High Risk of CNS Relapse
Jessica Hochberg, MD, Bradford Tallamy, BA, Prakash Satwani, Diane George, Monica Bhatia and Mitchell S. Cairo

112

Dexrazoxane Decreases Production of Induced Nitric Oxide by Doxorubicin
Jhon A. Guerra, MD, Myrnaliz Velazquez, MD, Pedro J. Santiago-Borrero, MD, Angel Roman-Franco, MD and Maria J. Crespo, PhD

114

Efficacy and Safety of Deferasirox (Exjade®) in Pediatric Patients with b-Thalassemia Major: 4.7-Year Extension Study Data
Antonio Piga, Gian Luca Forni, Antonis Kattamis, Christos Kattamis, Yesim Aydinok, Martha Rodriguez, Carole Paley and Renzo Galanello

116

Review of Four Years of Clinical Screening for Sickle Cell Vasclopathy Using Transcranial Doppler Ultrasonography
Nagina Parmar, PhD, Amanda Ciccolini, B.Sc., Laura Janzen, PhD, Fahd al-Manjoni, MD, Suzan Williams, Marcia Palmer, Doris Baxter, Alan Daneman and Melanie Kirby-Allen

118

Immunosuppressive Therapy without Granulocyte-Colony Stimulating Factor in Pediatric Acquired Aplastic Anemia
Rebecca J. Deyell, MD, Evan B. Shereck, MD and Kirk R. Schultz, MD

120

Report of a Rare Gene Mutation in a Patient with Non-Classical Diamond-Blackfan Anemia
Erin M. Cockrell, DO, Anthony Villella, MD and Jeffrey Hord, MD

122

Molecular Mechanisms of Myelodysplastic Syndrome in Severe Congenital Neutropenia
Ghada Kunter, MD

124

Transfusional Iron Overload in Acute Lymphoblastic Leukemia
Amanda B. Blair, M.D., Cristina Tarango, M.D., Daniel Bowers, M.D., Patrick Leavey, M.D. and Janna Journeycake, M.D.

126

Successful Treatment with Bone Marrow Transplant for a Patient with Fanconi Anemia, T-Cell Acute Lymphoblastic Leukemia, and Disseminated Aspergillosis
Terrie Flatt, DO, Karen Lewing, MD, Kathleen Neville, MD and Jignesh Dalal, MD

128

Dosing of rFVIIa in Pediatric Patients with Congenital Hemophilia B Complicated by Inhibitors to Factor IX: Analysis of Data from the Hemophilia and Thrombosis Research Society (HTRS) Registry (2004-2008)
Steven W. Pipe, MD, Caitlyn Wilke, MS and David L. Cooper, MD, MBA

130

Nonviral Gene Transfer to Hepatocytes Utilizing the Piggybac Transposon System: An Approach towards Hemophilia A Correction and Long Term Expression of Factor VIII
Janice M. Staber, MD, Erin Burnight, Litao Xie, Joseph Kaminski, MD and Paul B. McCray, Jr., MD

132

Baseline Thromboelastography (TEG) Reference Ranges for Infants and Children Presenting for Elective Cardiac Surgery
Michael Schmitz, MD, Edgar D. St. Amour, M.Sc., Megan M. Chang, MS, Kimo Stine, MD, Mark A. Austen, MS, Chanhee Jo, PhD, Pamela Killebrew, RNP and Robert J. Jaquiss, MD

134

Higher Doses of Recombinant Factor VIIa (rFVIIa) ≥250 Mcg/Kg in Pediatric Patients with Congenital Hemophilia Complicated by Inhibitors: The Hemophilia and Thrombosis Research Society Registry Experience (2004-2008)
Ellis J. Neufeld, MD, PhD, Craig M. Kessler, MD, Joan Cox Gill, MD, Caitlyn Wilke, MS and David L. Cooper, MD, MBA

136

The Use of Recombinant Factor VIIa Prior to Dental or Surgical Procedures in Children with Inherited Platelet Function Defects
Krupa M. Sivamurthy, MD

138

Predictors of Bleeding Disorders in Children: a Single Institution's Experience
Robert Sidonio, MD, Peter H. Shaw, MD and Sriya Gunawardena, MD

140

Utility of a Pediatric Bleeding Score to Identify Children with Pathological Bleeding
Nupur Mittal and Leonard A. Valentino, MD

142

Single Dose Recombinant Factor VIIa (rFVIIa) in Pediatric Congenital Hemophilia Inhibitor Patients: Analysis of Data Captured from the Hemophilia and Thrombosis Research Society Registry (HTRS) from 2004-2008
Rowena Punzalan, MD, Joan Cox Gill, MD, Craig M. Kessler, MD, Caitlyn Wilke, MS and David L. Cooper, MD, MBA

144

Subgaleal Hematoma from Hair Braiding Leads to the Diagnosis of Factor XIII Deficiency
Caroline Y. Hu, M.D., Rosanna Ricafort, M.D., Ravi Saksena, M.D. and Deepa Manwani, M.D.

146

Evaluation of the Anti-Tumor Activity of Vandetanib in Pediatric Acute Leukemias in Vitro
Margaret Macy, MD, Deborah DeRyckere, PhD and Lia Gore, MD

148

Dissecting the Role of CALM in Leukemogenesis: Elucidation of Functional Domains Required for Clathrin-Dependent Endocytosis
Paula B. Scotland, PhD, Amanda E. Conway, BS, Natasha L. Brooks, MS, Catherine P. Lavau, DVM, PhD and Daniel S. Wechsler, MD, PhD

150

Comparison of Leukemic and Controls Subjects Using Diffusion Tensor Imaging
Nancy K. Rollins, MD, Naomi Winick, MD, Barjor Gimi, Ph.D, Jonathon Chia, MS and Jerry Wang, Ph.D

152

LEUKEMIA STEM CELL NICHE: IL-1ß, TNF-α and MESENCHYMAL STROMA CO-CULTURE REDUCES U937 LEUKEMIA CELL GROWTH but INDUCES COBBLE STONE AREA FORMATION
Sarah Vaiselbuh, MD, Jeffrey M. Lipton, MD-PhD and Johnson M. Liu, MD

154

AHOPCA LH 1999 a Therapeutic Regimen for the Treatment of Children with Hodgkin Lymphoma (HL) in Central America (CA), a Report from the Asociación De Hemato-Oncología Pediátrica De Centro América (AHOPCA)
Pedro A. de Alarcón, Armando Peña, M.D., L. Fulgencio Baez, M.D., Soad Alabi, M.D. and Jose Carlos Barrantes, M.D.

156

Patterns of Death and Dying in Pediatric Oncology Patients: a Retrospective Review
Jodi L. Skiles, MD, Cynthia Bell, MSN, RN, Kamnesh R. Pradhan, MD, MS and Victoria Champion, DSN, RN, FAAN

158

Catheter Related Bloodstream Infections in Febrile Nonneutropenic Pediatric Oncology Patients
Michael J. Kelly, MD, Patrick M. Vivier, MD, PhD, Tali M. Panken and Cindy L. Schwartz, MD

160

Antibody Concentrations against Streptococcus Pneumoniae in Children after Completion of Treatment for Acute Leukaemia
Soonie R. Patel, MBChB, MRCP, MD, Jessica Bate, MBBS MA MRCPCH, Ray Borrow and Paul T. Heath, MBBS FRCPCH

162

Mutation Analysis of Potential Candidate Genes in Acute Megakaryocytic Leukemia Patients
Rukhmi Bhat, MD, Sebastien Malinge, PhD and John Crispino, PhD

164

Hemophagocytic Syndrome in Children with Chronic Granulomatous Disease
Chintan Parekh, MBBS, Thomas Hofstra, MD, Joseph Church and Thomas Coates

166

Are Pediatric Hodgkin Lymphoma Survivors at Greater Risk for Obesity - or Victims of a Pandemic?
Monika Metzger, Amanda Hoeffken, Kirsten K. Ness, PhD, Catherine Billups, Jianrong Wu, PhD, Matthew J. Krasin, MD, Sue Kaste, DO, Scott C. Howard and Melissa M. Hudson, MD

168

Cancer Stigma: Implications for the Care of Latino Adolescent and Young Adult Childhood Cancer Survivors
Jacqueline Casillas, MD, MSHS, Michelle Doose, MPH and Lonnie Zeltzer, MD

170

Parental Compliance with the Influenza Vaccination in Children with Cancer
Leslie S. Kersun, M.D., M.S.C.E., Mary Ingram, Anne F. Reilly, M.D., M.P.H. and Kathleen Sullivan, M.D., Ph.D.

172

Mechanisms of CALM-Dependent Acute Myeloid Leukemogenesis: Development of CALM-Inducible Cell Lines
Robert J. Greiner, MD, Sarah A. Goldstein, Paula B. Scotland, PhD, Catherine P. Lavau, DVM, PhD and Daniel S. Wechsler, MD, PhD

174

Renal Dysfunction in Children Receiving Methotrexate without Leucovorin during Interim Maintenance Therapy for Acute Lymphoblastic Leukemia
Pinki Kumari Prasad, MD, MPH and James A. Whitlock, MD

176

Routine Hospitalization after AML Chemotherapy May Not Improve Outcomes
Tiffany F. Lin, Carl E. Allen, MD, PhD, Bogdan R. Dinu, MD and Gladstone Airewele, MD

178

Endo-PAT to Assess Endothelial Dysfunction in Pediatric Sickle CELL Disease
Krupa M. Sivamurthy, MD, Carlton Dampier, MD, MaryLou MacDermott, RN, CRNP, Maureen Meier, RN, CCRC, Michele Cahill, RN and Lewis Hsu, MD, PhD

180

Prevalence and Risk Factors of Microalbuminuria in Children with Sickle Cell Disease
Vinu Jyothi, MBBS, Ibrahim Shatat, MD, MSCR, Eliabeth Rackoff, RN, Deborah Disco, Rn, MS, PNP, Sherron Jackson, MD and Ram Kalpatthi, MD

182

Adenotonsillectomy without Prior Transfusion in Children with Sickle Cell Disease
MaryEllen Cavalier, M.D., Zora R. Rogers, MD, Charles T. Quinn, MD and George R. Buchanan, MD

184

The Effect of Dietary Omega-3 Fatty Acids on the Severity of Sickle Cell Disease in Children
Kerin Arora, MPH, Deidre Dexter, RD and Philippa Sprinz, MD

186

Hemoglobin Kansas City: a New Unstable Alpha Chain Variant Hemoglobin Associated with Low Systemic Arterial Saturation
Erin M. Guest, M.D., Kathleen A. Neville, M.D., M.S., James D. Hoyer, M.D., Martin K. Safo, Ph.D., Uttam Garg, Ph.D., Carol J. Saunders, Ph.D., Osheiza Abdulmalik, DVM and David L. Zwick, M.D.

188

Age-Dependent Effects of Chronic Transfusion upon Fetal Hemoglobin Expression in Children with Sickle Cell Disease
Emily R. Meier, MD, Colleen Byrnes, MS, Maxine Weissman, MT, Pierre Noel, MD, Naomi L.C. Luban, MD and Jeffery L. Miller, MD

190

Use of Corticosteroids for Acute Chest Syndrome in Children with Sickle Cell Anemia: a Systematic Review
Hamayun Imran, MD, MSc, Evangeline Brown, MD, Roberto Bamba, MD, Trey Lemley, M.L.S, Laura K. Cousineau, M.L.S and Ram Kalpatthi, MD

192

Irinotecan and Temozolomide in Ewing Sarcoma: The Memorial Sloan-Kettering Experience
Denise A. Casey, M.D., Leonard H. Wexler, M.D., Melinda S. Merchant, M.D., Alexander J. Chou, M.D., Pamela R. Merola, M.D., Anita P. Price, M.D. and Paul A. Meyers, M.D.

194

Novel Genomic and Transcriptional Changes Identified in Progressive Pediatric Pilocytic Astrocytomas
Martha M. Stegner, MD, Tomoyuki Mashimo, PhD, Jun Guo, PhD, Linda R. Margraf, MD, Ryung S. Kim, PhD, Robert M. Bachoo, MD, PhD and Elizabeth A. Maher, MD, PhD

196

CCN3, Acting on the Notch Signal Transduction Cascade, Slows Glioma Cell Growth
Kartik Krishnan, MD, PhD, Stacey Rittmueller and Holly Dobrenen, B.S.

198

Inhibition of Medulloblastoma Progression in Vivo by Fibroblast Growth Factor
Eugene I. Hwang, MD, Marie P. Fogarty, PhD, John Dutton and Robert J. Wechsler-Reya, PhD

200

Role of VCAM-1 in Immune Evasion and Metastasis in Osteosarcoma
Stefanos Intzes, MD, Deborah Barkauskas, MS, Jay T. Myers, MS, Caryn Tong, MD, PhD and Alex Y. Huang, MD, PhD

202

Limitations in Physical Function among Adult Survivors of Childhood Brain Tumors
Kirsten K. Ness, PhD, Vikki G. Nolan, MPH, E. Brannon Morris, MD, Carrie R. Howell, MS, Laura S. Gilchrist, PhD and Joseph P. Neglia, MD MPH

204

Assessment of the Use of Serial Echocardiographic Screening in Survivors at Risk for Asymptomatic Late Onset Anthracycline Cardiomyopathy
Ibraheem Abosoudah, MD, Mark L. Greenberg, MB ChB, Lee Benson, MD, Kirsten K. Ness, PT, PhD and Paul Nathan, MD, MSc

206

PET-¹⁸ FDG and ¹²³ I-MIBG Scans Are Complementary in Assessing Response for Relapsed Neuroblastoma Patients
Denah R. Taggart, MD, Myo Han, MD, Alekist Quach, Susan Groshen, PhD, Wei Ye, Judith Villablanca, MD, Hollie Jackson, MD, Carina Mari Aparici, MD, David Carlson, MD, John M. Maris, MD, Randall Hawkins, MD and Katherine Matthay, MD

208

Clinicopathologic Comparison of Familial Versus Sporadic Atypical Teratoid/Rhabdoid Tumors (AT/RT) of the Central Nervous System: The Utah Experience
Carol S. Bruggers, MD, Phillip E. Barnette, MD, Theodore Pysher, MD, Zeinab Afify MD, Marion Walker, MD, Steven Bleyl, MD and Jaclyn Biegel, PhD

210

Surgical Treatment Problems in Patients with Bladder- / Prostate Rhabdomyosarcoma - a Report from the German Soft Tissue Sarcoma Study Group CWS-96
Guido Seitz, MD, Tobias Dantonello, MD, Christoph Int-Veen, Steven W. Warmann, MD, Ewa Koscielniak, MD and Joerg Fuchs, MD

212

Novel CIB1-Cdc42 Signaling Pathway in Neuroblastoma
Cassandra Moran, DO, Tina M. Leisner, PhD, Stephen P. Holly, PhD, Lisa Sharek, BS, Stephanie Hicks, PhD and Leslie V. Parise, PhD

214

Spinal and Paraspinal Ewing Tumors
Daniel J. Indelicato, MD, Sameer R. Keole, MD, Amir H. Shahlaee, MD, Christopher G. Morris, MS, C. Parker Gibbs, MD, Mark T. Scarborough, David W. Pincus, MD, PhD and Robert B. Marcus, MD

216

Choroid Plexus Tumor Therapy, Clinical Outcome and Familial Cancer Association: The Childrens Hospital Los Angeles (CHLA) Experience, 1991-2008
Alexa E. Gozali, B.A., Lisa Shane, M.D., Gordon McComb, M.D., Mark Krieger, M.D., Ignacio Gonzalez, M.D., Floyd Gilles, M.D., Judith Villablanca, MD, Anat Erdreich-Epstein, M.D., Ph.D., Robert S. Lavey, M.D., M.P.H., Uri Tabori, M.D., Adam Shlien, B.Sc., David Malkin, M.D. and Jonathan Finlay

218

Hereditary Cancer Risk Assessment in a Pediatric Oncology Follow up Clinic
Sara C. Knapke, MS, Judy Correll, RN, CNP, Rajaram Nagarajan, MD, MS and Karen C. Burns, MD, MS

220

Residual Mass Disease in Intermediate Risk Stage 4 Neuroblastoma: Using Histopathology to Assess Outcome and Further Treatment
Allison Ast, Hiro Shimada, MD, Judith Villablanca, MD, Hollie Jackson, MD and Araz Marachelian, MD

222

Using Meta-Analysis of Publicly Available Genomic Expression Datasets to Identify a Gene Expression Signature of Metastasis in Osteosarcoma
Marla A. Hawkins, M.D., Alexander Yu, Susan G. Hilsenbeck, Ph.D., Rudy Guerra, Ph.D., Ching Lau, M.D., Ph.D. and Chris T. Man, Ph.D.

224

Acinic Cell Carcinoma: Cut It out..... Then What?
Paul J. Gibson, MD, FRCPC, Vito Forte, Gino R. Somers, Normand P. Laperriere and Ronald M. Grant

226

Pediatric Preclinical Testing Initiative
Aoife Kilcoyne, MB BCh BAO, Amanda T. Mc Cleish, Eri Taniguchi, Koichi Nishijo, Laura Hampton and Charles Keller

228

Long Term Survival in Disseminated Choroid Plexus Carcinoma without Irradiation
Soumen Khatua, MD, Alan Lavian, Girish Dhall, MD, Judith Villablanca, MD, Alexa Gozali and Jonathan Finlay, MD

230

Examination of Difficulties with School Reentry in Cancer Survivors
Renee Gardner, MD, Maria C. Velez, Vijay Kata and Harold Jimenez, BS

232

Renal Carcinoma in Neuroblastoma Survivors
Crystal Yu, Judith Villablanca, MD, Hiro Shimada, MD and Araz Marachelian, M.D.

234

Thymic Carcinoma in Children and Young Adults: Case Series Report and Review of Literature
Vivek Subbiah, MD, Michael Rytting, MD, Robert Wells, MD, Pete Anderson, MD PhD and Cynthia E. Herzog

236

The Effect of Notch Blockade with DBZ, a Gamma-Secretase Inhibitor, on the in Vitro and in Vivo Growth of a Neuroblastoma Cell Line
Jennifer Freed, M.D., Sonia Hernandez, Jessica J. Kandel, M.D. and Darrell Yamashiro, M.D., PhD.

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